ghk-cu vs bpc-157
updated
ghk-cu (tier S) vs bpc-157 (tier A): what each is, why each got its grade, half-life and source counts side by side.
ghk-cu · tier S
the copper peptide with the strongest skin evidence in the catalog. topical record first, injectable story thinner.
tier rationale
the most studied cosmetic peptide in history. pickart 1973: young plasma applied to aged liver cells made them behave young. five decades of topical research on collagen, wound healing, inflammation. cleanest safety profile in the catalog after 40+ years of cosmetic use. S because topical efficacy is documented and safety is exceptional. the asterisk: injectable GHK-Cu has a much thinner human evidence base.
bpc-157 · tier A
the contested repair peptide. strong animal data, thin human trials, huge community gravity.
tier rationale
A-tier because the preclinical evidence is extraordinary and the community signal is persistent. Not S-tier because drug-grade human evidence does not exist, long-term human safety is not characterized, and the single-lab concentration matters. If independent controlled trials ever hold up, the tier can move. Until then, A is the ceiling.
at a glance
| ghk-cu | bpc-157 | |
|---|---|---|
| tier | S | A |
| category | skin / cosmetic / healing / tissue | healing / tissue |
| sources | 30 | 37 |
| claims evaluated | 7 | 9 |
| half-life | plasma: minutes | short |
| dosing data | yes | yes |
reptides grades the research record and cites the literature behind every call. research reference only; not medical advice.