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the retatrutide titration schedule from the TRIUMPH phase 3 trial

the 16-week ladder used in TRIUMPH phase 3, pre-approval.

the short answer

  • TRIUMPH-1: 28.3% mean weight loss at phase 3
  • ladder: 2 → 4 → 6 → 9 → 12 mg weekly, 12mg by week 17
  • triple agonist (GLP-1 + GIP + glucagon)

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