the FDA-approved tirzepatide titration schedule (Mounjaro and Zepbound)

published

the FDA-label 6-step ladder, 4 weeks per step.

the short answer

  • 6 steps: 2.5 → 5 → 7.5 → 10 → 12.5 → 15 mg weekly
  • same titration for Mounjaro and Zepbound
  • sourced from FDA PI + SURMOUNT-1 side-effect peaks

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reptides grades the research record and cites the literature behind every call. research reference only; not medical advice.