the FDA-approved tirzepatide titration schedule (Mounjaro and Zepbound)
the FDA-label 6-step ladder, 4 weeks per step.
the short answer
- 6 steps: 2.5 → 5 → 7.5 → 10 → 12.5 → 15 mg weekly
- same titration for Mounjaro and Zepbound
- sourced from FDA PI + SURMOUNT-1 side-effect peaks
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reptides grades the research record and cites the literature behind every call. research reference only; not medical advice.