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liraglutide

A once-daily GLP-1 receptor agonist sold under separate Saxenda and Victoza labels.

tier S · weight loss · 8.4 kg SCALE mean weight change

verdict

Liraglutide has direct obesity, diabetes, cardiovascular, and adolescent evidence, with daily dosing and product-specific labels.

if you are comparing Saxenda and Victoza: Both contain liraglutide and use once-daily subcutaneous prefilled pens. Saxenda is the weight-management product; Victoza is the type 2 diabetes product with a cardiovascular-risk indication.

if you are comparing it with semaglutide: STEP 8 directly compared weekly semaglutide with daily liraglutide in 338 adults without diabetes. Mean weight change at 68 weeks was -15.8 percent versus -6.4 percent.

if you are asking why it still matters: SCALE established adult obesity efficacy, LEADER established cardiovascular benefit in high-risk type 2 diabetes, and a randomized trial established an adolescent obesity evidence base.

This is an evidence record, not a dosing recommendation.

what it is

Liraglutide is a GLP-1 receptor agonist with an approximately 13-hour elimination half-life after subcutaneous administration. Saxenda and Victoza are separate ready-to-use pen products with distinct indications and safety records.

key facts

  • molecular formula: C172H265N43O51
  • molecular weight: ~3751.2 Da
  • amino acids: 31 aa
  • half-life: ~13 hours
  • type: acylated GLP-1 receptor agonist

frequently asked questions

What is the difference between Saxenda and Victoza?

They contain the same active molecule but have separate labels. Saxenda is the weight-management product. Victoza is the type 2 diabetes product and includes a cardiovascular-risk indication for adults with established cardiovascular disease.

How long is liraglutide's half-life?

The current labels report an elimination half-life of approximately 13 hours after subcutaneous administration.

Does liraglutide have adolescent evidence?

Yes. A 251-participant randomized trial studied adolescents aged 12 to under 18 years with obesity and poor response to lifestyle therapy.

reptides grades the research record and cites the literature behind every call. research reference only; not medical advice.

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