reptides › dihexa vs semax

dihexa vs semax

dihexa (D-tier) vs semax (B-tier). mechanism, trials, claims vs data, dosing literature. side-by-side reference.

dihexa — tier D

rodent nootropic with zero human trials and a mechanism that's a named oncology concern.

rodent nootropic with zero human trials and a mechanism (c-Met activation) that's a named oncology proliferation pathway.

HGF mimetic · research · half-life not characterized in humans; oral bioavailability demonstrated in rodent models · focus

semax — tier B

russian nootropic. approved there, not here. for focus, stroke recovery, and cognitive decline. real mechanism, thin US trials.

Russian nootropic. approved there since the 1990s. BDNF upregulation within 30 minutes of an intranasal dose, effect persists 24+ hours.

Russia '82 stroke registry · half-life minutes in plasma; effects persist for hours due to CNS penetration and BDNF induction cascade · focus

at a glance

  • dihexa: tier D · HGF mimetic · research
  • semax: tier B · Russia '82 stroke registry

reptides grades the research record and cites the literature behind every call. research reference only; not medical advice.