Oxandrolone vs Oxymetholone

updated

Oxandrolone (tier S) vs Oxymetholone (tier S): what each is, why each got its grade, half-life and source counts side by side.

Oxandrolone · tier S

Anavar is oral oxandrolone, an anabolic-androgenic steroid used in bodybuilding for muscle, strength, and a leaner or harder look.

tier rationale

S grades the certainty of the identity, human PK, and randomized outcome record; it is not a safety or current-approval grade.

Oxymetholone · tier S

an oral 17-alpha-alkylated anemia drug with legal FDA approval but no active US marketing, controlled human lean-mass data, severe dose-related hepatic toxicity, and animal-only terminal half-life.

tier rationale

S tier reflects clear identity, an FDA-reviewed label, and multiple controlled human outcome datasets. Severe hepatic and lipid toxicity, discontinued marketing, and missing human terminal PK are stated as central facts, not hidden by the grade.

at a glance

OxandroloneOxymetholone
tierSS
categoryandrogens / anabolicsandrogens / anabolics
sources137
claims evaluated43
half-life10.4 hours in younger volunteers and 13.3 hours in older adults in the historical Oxandrin labelno validated human terminal half-life; 5.56 hours in male F344/N rats after 30 mg/kg oral gavage
dosing datayesyes

reptides grades the research record and cites the literature behind every call. research reference only; not medical advice.