RU58841 vs Finasteride

RU58841 (C-tier) vs Finasteride (S-tier). mechanism, trials, evidence boundaries, dosing literature. side-by-side reference.

RU58841 · tier C

RU58841 is a topical nonsteroidal androgen-receptor antagonist research chemical with macaque and human-scalp-graft signals, plus two completed human-study registrations without published results.

Topical RU58841 produced hair signals in a stumptailed-macaque model and in human scalp grafts carried by nude mice. Those preclinical results cannot answer how well it works, how it is absorbed, or how safe it is on a person's scalp.

0 located published human outcome reports · half-life unknown; no located published human PK result · skin

Finasteride · tier S

Finasteride is an oral type-II 5-alpha-reductase inhibitor with an FDA-approved male-pattern-hair-loss indication in men and large randomized hair-count trials.

Oral finasteride 1 mg slows progression and improves measured scalp-hair outcomes in men with androgenetic alopecia while treatment continues. That record does not transfer to compounded topical products, women, children, or every pattern of hair loss.

+107 hairs placebo-adjusted one-year vertex-area difference · half-life about 5 to 6 h in adults aged 18 to 60 after oral tablets; longer in older adults · skin

at a glance

• RU58841: tier C · 0 located published human outcome reports
• Finasteride: tier S · +107 hairs placebo-adjusted one-year vertex-area difference

reptides grades the research record and cites the literature behind every call. research reference only; not medical advice.