aod 9604 vs semaglutide
aod 9604 (D-tier) vs semaglutide (S-tier). mechanism, trials, evidence boundaries, dosing literature. side-by-side reference.
aod 9604 — tier D
HGH fragment. went to phase 2b for obesity. failed. the data says it doesn't work.
HGH fragment. went to phase 2b for obesity. failed. the data says it doesn't work for the marketed indication.
frag 176-191 phase 2b · failed · half-life plasma half-life extended versus unmodified fragment; lipolytic effects acute and dose-dependent · weight loss
semaglutide — tier S
A GLP-1 receptor agonist with current US injection and oral products for distinct labeled uses.
Strong obesity, cardiovascular, kidney, and MASH evidence, but each result belongs to its own product, route, population, and label.
14.9% STEP 1 mean weight change · half-life ~1 week · weight loss
at a glance
- aod 9604: tier D · frag 176-191 phase 2b · failed
- semaglutide: tier S · 14.9% STEP 1 mean weight change
reptides grades the research record and cites the literature behind every call. research reference only; not medical advice.
