aod 9604 vs semaglutide

aod 9604 (D-tier) vs semaglutide (S-tier). mechanism, trials, claims vs data, dosing literature. side-by-side reference.

aod 9604 — tier D

HGH fragment. went to phase 2b for obesity. failed. the data says it doesn't work.

HGH fragment. went to phase 2b for obesity. failed. the data says it doesn't work for the marketed indication.

frag 176-191 phase 2b · failed · half-life plasma half-life extended versus unmodified fragment; lipolytic effects acute and dose-dependent · weight loss

semaglutide — tier S

ozempic. wegovy. rybelsus. the GLP-1 drug that made obesity a pharmacology problem.

the GLP-1 that broke containment. ozempic, wegovy, rybelsus. same molecule, three labels.

14.9% STEP 1 wt loss · half-life ~1 week (acylated) · weight loss

at a glance

• aod 9604: tier D · frag 176-191 phase 2b · failed
• semaglutide: tier S · 14.9% STEP 1 wt loss

reptides grades the research record and cites the literature behind every call. research reference only; not medical advice.