ipamorelin vs ghrp-6
updated
ipamorelin (tier C) vs ghrp-6 (tier D): what each is, half-life and source counts side by side.
ipamorelin · tier C
Ipamorelin is a synthetic pentapeptide ghrelin-receptor agonist. People seek it for sleep, recovery, and body composition, but direct human studies measured an acute intravenous GH pulse and a negative ileus outcome.
tier rationale
C reflects dose-related human growth-hormone release plus a 114-person clinical efficacy trial that missed its primary endpoint. No controlled study measured the marketed fitness, recovery, or sleep outcomes.
ghrp-6 · tier D
older sibling of GHRP-2. even more appetite, same cortisol issues. ipamorelin made it obsolete.
tier rationale
D-tier for the same reason as GHRP-2: a cleaner alternative (ipamorelin) exists at the same price and availability. Not F-tier because GHRP-6 does what it claims, pulsatile GH release, real appetite stimulation. The tier is about obsolescence, not failure. If ipamorelin didn't exist, this compound would be B-tier with specific cautions. With ipamorelin on the market and costing the same, the surviving niche is appetite stimulation, not a better GH-secretagogue profile.
at a glance
| ipamorelin | ghrp-6 | |
|---|---|---|
| tier | C | D |
| category | gh / growth | gh / growth |
| sources | 11 | 15 |
| claims evaluated | n/a | 5 |
| half-life | about 2 hours after intravenous infusion | approximately 15-60 minutes; short-acting pulsatile effect |
| dosing data | yes | yes |
reptides grades the research record and cites the literature behind every call. research reference only; not medical advice.