sermorelin vs ipamorelin

sermorelin (B-tier) vs ipamorelin (C-tier). mechanism, trials, evidence boundaries, dosing literature. side-by-side reference.

sermorelin · tier B

Sermorelin is amidated GHRH(1-29). Its direct efficacy record is pediatric, while current adult sleep, recovery, and body-composition claims remain unproven.

People seek sermorelin for sleep, recovery, and body composition. An open-label pediatric study reported faster growth among 86 efficacy-evaluable children, not those adult outcomes.

86 efficacy-evaluable children · half-life 4.3 plus or minus 1.4 minutes after intravenous administration · growth hormone

Ipamorelin is a synthetic pentapeptide ghrelin-receptor agonist. People seek it for sleep, recovery, and body composition, but direct human studies measured an acute intravenous GH pulse and a negative ileus outcome.

Ipamorelin released GH after intravenous infusion, but it has no controlled human sleep, recovery, muscle, or body-composition outcome trial. Its selectivity case comes mainly from swine and rodent work.

114 patients in the negative ileus trial · half-life about 2 hours after intravenous infusion · growth hormone

at a glance

sermorelin: tier B · 86 efficacy-evaluable children
ipamorelin: tier C · 114 patients in the negative ileus trial

reptides grades the research record and cites the literature behind every call. research reference only; not medical advice.