5-amino-1mq vs mots-c
5-amino-1mq (C-tier) vs mots-c (B-tier). mechanism, trials, evidence boundaries, dosing literature. side-by-side reference.
5-amino-1mq — tier C
5-amino-1MQ is a small molecule NNMT inhibitor, not a peptide. People seek it for fat loss, but every administration and outcome study located for this review was in animals.
Subcutaneous mouse studies found lower weight or fat gain. There is no human administration evidence, so human benefit, adverse effects, and a safe exposure are unknown.
NNMT inhibitor, preclinical · half-life no human pharmacokinetic measurement; rat and mouse values differ by route and are kept separate · weight loss
mots-c — tier B
mitochondrial peptide your body makes during exercise. restores metabolic health in mice. never given to a person in a trial.
a mitochondrial-derived peptide. AMPK activation, mouse data is strong and replicated. no trial has ever given it to a person, and the one registry record saying otherwise is fabricated.
16 aa mitochondrial-derived · half-life minutes in plasma; functional effects persist hours via downstream gene expression · focus
at a glance
- 5-amino-1mq: tier C · NNMT inhibitor, preclinical
- mots-c: tier B · 16 aa mitochondrial-derived
reptides grades the research record and cites the literature behind every call. research reference only; not medical advice.