5-amino-1mq vs mots-c

5-amino-1mq (C-tier) vs mots-c (B-tier). mechanism, trials, claims vs data, dosing literature. side-by-side reference.

5-amino-1mq — tier C

small-molecule NNMT inhibitor. reproducible mouse data, zero published human trials, recent community discussion driven primarily by vendor-affiliated commercial promotion.

NNMT inhibitor · research · half-life not characterized in humans; mouse oral bioavailability adequate in published animal studies · weight loss

mots-c — tier B

mitochondrial peptide your body makes during exercise. restores metabolic health in mice. human trials just starting.

a mitochondrial-derived peptide. AMPK activation, mouse data is strong and replicated. the first-in-human parent-molecule trial just started April 2026.

16 aa mitochondrial-derived · half-life minutes in plasma; functional effects persist hours via downstream gene expression · focus

at a glance

5-amino-1mq: tier C · NNMT inhibitor · research
mots-c: tier B · 16 aa mitochondrial-derived

reptides grades the research record and cites the literature behind every call. research reference only; not medical advice.